Paul Tracy will stand in for Mario Moraes at KV Racing this weekend at Mid-Ohio, following the death of Moraes' father this week.
Moraes will remain in Brazil with his family this weekend and will be replaced by Tracy, who has raced for the team four times already this season.
"I want to thank KV Racing and Mario for thinking of me during this unfortunate situation," said Tracy. "It will be a privilege to drive the #5 entry and I want to dedicate this weekend to achieving the best result possible in honour of Mario and the entire Moraes family."
A statement released by KV co-owners Kevin Kalkhoven and Jimmy Vasser said: "This is a very sad occasion and on behalf of the entire KV Racing Technology organisation we extend our sympathy and condolences to Mario and his family.
"After lengthy internal discussions, and in consultation with Mario, we decided the best course of action was to have Paul, who has driven for the team and is familiar with our systems and personnel, step in and drive this weekend."